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Understanding Your Pathology Report: A Comprehensive Step-By-Step Guide




If you’ve had surgery or a biopsy, the biological sample from your procedure will be sent to a pathologist working in a laboratory. The pathologist will study your sample and create a pathology report providing important information about what was found in your sample. Your pathology report will be reviewed carefully by your oncology team, and you should discuss it with your doctors to ensure you understand your specific situation.

Before you receive or review your pathology report, however, you may be looking for more information about what exactly this report is and what you can expect it to contain. You may feel some anxiety waiting for your pathology report, and deciphering the medical jargon and dense information can be daunting. Continue reading to understand the process and your pathology report in a simple, step-by-step format.


What Is a Pathology Report?

A pathology report is a document that contains the findings of a pathologist who has examined a patient’s biological samples under a microscope. The samples are usually obtained through biopsy, surgery, or a medical examination and can include findings from body tissues, fluids, or cells.


Your pathology report provides valuable insight into the nature of your disease. It includes detailed information about the type, grade, and extent of your cancer, as well as the margins of the removed tissue. Pathologists play a critical role in diagnosing diseases like cancer, and their reports guide physicians in determining the appropriate course of treatment.


Why Understanding Your Pathology Report Matters

Understanding your pathology report empowers you to participate actively in your healthcare decisions with your oncology team. It helps you grasp the severity and nature of your condition and set expectations for your treatment. For more insights on why understanding your pathology report is crucial, refer to resources provided by The American Cancer Society.


Understanding the Structure of Your Pathology Report

A pathology report usually contains the following sections:

  • Patient Information: Your name, patient ID, date of birth, and the name of the physician who requested the test.

  • Specimen Information: The type and location of the sample, how and when pathology received it, and who provided it. It may include information about the margins — the edges of tissue that was removed during the biopsy or surgery. Since the goal of surgery is to remove all of the cancerous tissue, it’s vital to ensure that the margins are clear or negative (meaning that no cancer cells are detected on the edges). If any lymph nodes were removed during the procedure, the pathology report will also state whether cancer cells were found in them.

  • Gross Description: What the pathologist observed with the naked eye, including the color, size, and weight of the sample.

  • Microscopic Description: A description of what the pathologist observed under the microscope, including cell structures and abnormalities.

  • Diagnosis: The pathologist’s interpretation of the findings and the final diagnosis.


Reading Your Pathology Report

Now that you know what a pathology report includes, here’s a guide to understanding your report:

  • Verify Patient Information: Ensure that the patient details are correct. Mistakes, although rare, can happen.

  • Understand the Specimen: Knowing what type of specimen was taken and where it was taken from can give context to the report.

  • Gross Description: While this section can be technical, look for descriptors of size, shape and color, which can give you an idea of the sample’s normality.

  • Microscopic Description: This section might be complex, containing detailed observations of cellular structures. Look for terms like benign, malignant, normal, abnormal, etc. to get a sense of what was found.

  • Interpret the Diagnosis: Again, the final diagnosis as stated by the pathologist might be technical and challenging to understand. You can use reliable medical dictionaries like MedlinePlus to understand them.


Remember, it’s essential to discuss these findings with your healthcare provider to fully understand your condition and to determine the next steps in your care.


Count On Us for Information, Resources, and Support

Understanding your pathology report is a critical step in managing your health. The knowledge contained in your report can help you better understand your diagnosis. This will empower you to navigate and make informed decisions about your treatment. Consult with your healthcare provider for clarifications and concerns. Please contact us if you have questions about speaking with your doctor regarding your pathology report!


Whether you’re newly diagnosed with breast cancer, are navigating survivorship, or are the loved one of someone experiencing breast cancer, you can count on SurvivingBreastCancer.org to keep you informed. We provide educational information to help you better understand symptoms, testing, treatment options, surgery, etc., and podcasts that feature professionals, advocates, and caregivers that share valuable information.


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Note: This article is designed to provide general information and not meant to replace professional medical advice. Always discuss your pathology reports with your healthcare provider.


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